Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.56 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22922181 | 0.87 | CYP4F2 (0.59) | CYP4F2CYP4A11F2RL1ADRB2ADRB1 | |
| SCHEMBL23582843 | 0.86 | CYP4F2 (0.66) | CYP4F2CYP4A11F2RL1ALDH1A1LMNA | |
| SCHEMBL14422859 | 0.85 | CYP4F2 (0.63) | CYP4F2CYP4A11CA2ALDH1A1LMNA | |
| SCHEMBL11243916 | 0.84 | CYP4F2 (0.58) | CYP4F2CYP4A11F2RL1ADRB2ADRB1 | |
| SCHEMBL8988602 | 0.84 | CYP4F2 (0.58) | CYP4F2CYP4A11CA2F2RL1ADRB2 | |
| SCHEMBL2569441 | 0.83 | L3MBTL1 (0.55) | CYP4F2CYP4A11F2RL1ADRB2ADRB1 | |
| SCHEMBL5012302 | 0.82 | PARP10 (0.48) | CYP4F2CYP4A11CA2F2RL1ADRB2 | |
| SCHEMBL2851609 | 0.81 | LOXL2 (0.56) | CYP4F2CYP4A11F2RL1ADRB2ADRB1 | |
| SCHEMBL223653 | 0.81 | CYP4F2 (0.50) | CYP4F2CYP4A11F2RL1ADRB2ADRB1 | |
| SCHEMBL26517824 | 0.81 | TAAR1 (0.52) | CYP4F2CYP4A11F2RL1ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4074701-B1 | NOVEL AMIDE DERIVATIVE USEFUL AS DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITOR, AND USE THEREOF | LG CHEMICAL LTD (KR) | 2023-12-13 | — | — | EP | disclosed |
| WO-2021133038-A1 | NOVEL AMIDE DERIVATIVE USEFUL AS DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITOR, AND USE THEREOF | 주식회사 엘지화학 | 2021-07-01 | — | — | WO | disclosed |