Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | PRKCI | P41743 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23599373 | 0.89 | CYP3A4 (0.41) | MAOAMAOBPRKCILMNAALDH1A1 | |
| SCHEMBL31185504 | 0.89 | CYP3A4 (0.41) | MAOAMAOBPRKCILMNAALDH1A1 | |
| SCHEMBL23189098 | 0.83 | BRD4 (0.43) | MAOAMAOBPRKCILMNAALDH1A1 | |
| SCHEMBL11466992 | 0.81 | BRD4 (0.46) | MAOAMAOBPRKCILMNAALDH1A1 | |
| SCHEMBL11260702 | 0.81 | MAOA (0.52) | MAOAMAOBPRKCILMNAALDH1A1 | |
| SCHEMBL10750551 | 0.78 | BRD4 (0.41) | MAOAMAOBPRKCIALDH1A1MAPT | |
| SCHEMBL21098729 | 0.78 | MAOA (0.49) | MAOAMAOBPRKCILMNAALDH1A1 | |
| SCHEMBL29709012 | 0.78 | MAOA (0.49) | MAOAMAOBPRKCILMNAALDH1A1 | |
| SCHEMBL31217240 | 0.78 | MAOA (0.49) | MAOAMAOBPRKCILMNAALDH1A1 | |
| SCHEMBL21052196 | 0.77 | PTGS2 (0.53) | MAOAMAOBPRKCILMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022262686-A1 | KRAS G12D INHIBITORS | JINGRUI BIOPHARMA CO., LTD. (CN) | 2022-12-22 | — | — | WO | disclosed |
| WO-2021129827-A1 | BENZO FUSED RING-BASED COMPOUND | 南京明德新药研发有限公司 | 2021-07-01 | — | — | WO | disclosed |