Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKZ | Q13574 | 20/20 | 0.48 |
| ▸ | DGKA | P23743 | 11/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23527125 | 0.87 | DGKZ (0.47) | DGKZDGKA | |
| SCHEMBL23564307 | 0.87 | DGKZ (0.48) | DGKZDGKA | |
| SCHEMBL30900943 | 0.87 | DGKZ (0.47) | DGKZDGKA | |
| SCHEMBL23564388 | 0.87 | DGKZ (0.47) | DGKZDGKA | |
| SCHEMBL23600164 | 0.87 | SCD (0.47) | DGKZDGKA | |
| SCHEMBL23600323 | 0.86 | MEN1 (0.42) | DGKZDGKA | |
| SCHEMBL23526866 | 0.85 | DGKZ (0.48) | DGKZDGKA | |
| SCHEMBL26558325 | 0.85 | DGKZ (0.57) | DGKZDGKA | |
| SCHEMBL23527071 | 0.80 | DGKZ (0.56) | DGKZDGKA | |
| SCHEMBL23526966 | 0.80 | DGKZ (0.56) | DGKZDGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133750-A1 | SUBSTITUTED BICYCLIC PIPERIDINE DERIVATIVES USEFUL AS T CELL ACTIVATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-07-01 | — | — | WO | disclosed |