Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 5/20 | 0.47 |
| ▸ | DGKZ | Q13574 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23600259 | 0.87 | DGKZ (0.48) | DGKZDGKA | |
| SCHEMBL30900998 | 0.87 | DGKZ (0.43) | SCDDGKZMEN1KMT2ADGKA | |
| SCHEMBL30900942 | 0.87 | DGKZ (0.43) | SCDDGKZMEN1KMT2AACSL1 | |
| SCHEMBL23564310 | 0.87 | DGKZ (0.43) | SCDDGKZMEN1KMT2AACSL1 | |
| SCHEMBL23526938 | 0.87 | DGKZ (0.43) | SCDDGKZMEN1KMT2AACSL1 | |
| SCHEMBL23527134 | 0.87 | DGKZ (0.43) | SCDDGKZMEN1KMT2ADGKA | |
| SCHEMBL23527052 | 0.87 | DGKZ (0.43) | SCDDGKZMEN1KMT2ADGKA | |
| SCHEMBL26560280 | 0.83 | DGKZ (0.45) | SCDDGKZDGKA | |
| SCHEMBL23526945 | 0.81 | MEN1 (0.43) | SCDDGKZMEN1KMT2ATP53 | |
| SCHEMBL31133788 | 0.81 | MEN1 (0.43) | SCDDGKZMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133750-A1 | SUBSTITUTED BICYCLIC PIPERIDINE DERIVATIVES USEFUL AS T CELL ACTIVATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-07-01 | — | — | WO | disclosed |