Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 14/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 10/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28906618 | 0.73 | MAPT (0.45) | DPP7FDPS | |
| SCHEMBL19090909 | 0.72 | — | — | |
| SCHEMBL500539 | 0.72 | KDM4E (0.44) | DPP4DPP7DPP8DPP9FDPS | |
| SCHEMBL15273354 | 0.70 | CHRM5 (0.40) | — | |
| SCHEMBL4856742 | 0.70 | KDM4E (0.47) | — | |
| SCHEMBL3762753 | 0.69 | ALDH1A1 (0.36) | — | |
| SCHEMBL471732 | 0.69 | DPP4 (0.73) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL2361923 | 0.68 | KDM4E (0.40) | — | |
| SCHEMBL13076968 | 0.68 | — | — | |
| SCHEMBL5090586 | 0.67 | FDPS (0.42) | DPP4DPP7DPP8DPP9FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2533645-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | The Johns Hopkins University (US) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011100373-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | THE JOHNS HOPKINS UNIVERSITY (US) | 2011-08-18 | — | — | WO | disclosed |