Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | PTAFR | P25105 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | PER2 | O15055 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576692 | 0.92 | DHODH (0.36) | DHODHKDM4EPTAFRRETMAPT | |
| SCHEMBL29909342 | 0.92 | DHODH (0.36) | DHODHKDM4EPTAFRRETMAPT | |
| SCHEMBL30047203 | 0.91 | DHODH (0.36) | DHODHKDM4EPTAFRRETMAPT | |
| SCHEMBL23601264 | 0.89 | DHODH (0.36) | DHODHPTAFRPER2BCHEACHE | |
| SCHEMBL23601262 | 0.89 | DHODH (0.37) | DHODHKDM4ERXRARXRBRXRG | |
| SCHEMBL23601313 | 0.87 | PTAFR (0.33) | DHODHPTAFRBCHEACHEGRIN1 | |
| SCHEMBL29909933 | 0.87 | STAT3 (0.40) | KDM4EPTAFRMAPT | |
| SCHEMBL23576864 | 0.87 | STAT3 (0.40) | KDM4EPTAFRMAPT | |
| SCHEMBL23601077 | 0.85 | DHODH (0.33) | DHODHKDM4EPTAFRMAPTPER2 | |
| SCHEMBL23601964 | 0.85 | DHODH (0.35) | DHODHPTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |