SCHEMBL23601964

SCHEMBL23601964

Cc1nnc2nc(N3CCCc4c(Br)cc(F)cc43)c3cc(F)ccc3n12

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.35
PTAFR P25105 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29909267 1.00 DHODH (0.35) DHODHPTAFR
SCHEMBL23601264 0.92 DHODH (0.36) DHODHPTAFR
SCHEMBL29909342 0.89 DHODH (0.36) DHODHPTAFR
SCHEMBL23576692 0.89 DHODH (0.36) DHODHPTAFR
SCHEMBL23576719 0.89 PTAFR (0.32) PTAFR
SCHEMBL29909269 0.89 PTAFR (0.32) PTAFR
SCHEMBL23601078 0.85 DHODH (0.39) DHODHPTAFR
SCHEMBL23601313 0.84 PTAFR (0.33) DHODHPTAFR
SCHEMBL30047203 0.83 DHODH (0.36) DHODHPTAFR
SCHEMBL23601560 0.82 DHODH (0.32) DHODHPTAFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117736207-A Diacylglycerol kinase modulating compounds 卡尔那生物科学株式会社 2024-03-22 CN disclosed
CN-115362003-B Diacylglycerol kinase modulating compounds 卡尔那生物科学株式会社 2024-03-22 CN disclosed
WO-2021130638-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS CARNA BIOSCIENCES, INC. (JP) 2021-07-01 WO disclosed