Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 7/20 | 0.36 |
| ▸ | PTAFR | P25105 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576692 | 1.00 | DHODH (0.36) | DHODHPTAFRRETKDM4EHTR6 | |
| SCHEMBL23601078 | 0.92 | DHODH (0.39) | DHODHPTAFRRETKDM4EMAPT | |
| SCHEMBL30047203 | 0.90 | DHODH (0.36) | DHODHPTAFRRETKDM4EMAPT | |
| SCHEMBL29909267 | 0.89 | DHODH (0.35) | DHODHPTAFR | |
| SCHEMBL23601964 | 0.89 | DHODH (0.35) | DHODHPTAFR | |
| SCHEMBL24814616 | 0.89 | HTR6 (0.35) | DHODHHTR6 | |
| SCHEMBL30047454 | 0.89 | HTR6 (0.35) | DHODHHTR6 | |
| SCHEMBL23576719 | 0.88 | PTAFR (0.32) | PTAFR | |
| SCHEMBL29909269 | 0.88 | PTAFR (0.32) | PTAFR | |
| SCHEMBL30047169 | 0.87 | DHODH (0.32) | DHODHKDM4EHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-4359415-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022271684-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-12-29 | — | — | WO | disclosed |
| CN-115362003-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2022-11-18 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |