Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | NOS2 | P35228 | 3/20 | 0.32 |
| ▸ | PER2 | O15055 | 1/20 | 0.32 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.32 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601460 | 0.90 | TP53 (0.35) | TP53ALDH1A1TSHRMAPK1MAPT | |
| SCHEMBL23601471 | 0.89 | MAPT (0.31) | MAPTSMN1; SMN2KDM4E | |
| SCHEMBL23601253 | 0.84 | MAPT (0.41) | TP53ALDH1A1TSHRMAPK1MAPT | |
| SCHEMBL23601054 | 0.84 | MAPT (0.33) | MAPTNOS2 | |
| SCHEMBL23601449 | 0.83 | — | — | |
| SCHEMBL23576811 | 0.82 | — | — | |
| SCHEMBL29909850 | 0.82 | — | — | |
| SCHEMBL23601010 | 0.81 | CRY1 (0.33) | TP53MAPTSMN1; SMN2CRY1CRY2 | |
| SCHEMBL23601237 | 0.80 | MAPT (0.34) | MAPTSMN1; SMN2CRY1CRY2POLB | |
| SCHEMBL23576855 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |