Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CSF1R | P07333 | 5/20 | 0.37 |
| ▸ | EGFR | P00533 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601248 | 0.84 | TP53 (0.34) | MAPTSMN1; SMN2TSHRTP53KDM4E | |
| SCHEMBL23576740 | 0.83 | — | — | |
| SCHEMBL29909375 | 0.83 | — | — | |
| SCHEMBL23601558 | 0.83 | — | — | |
| SCHEMBL23601764 | 0.80 | MAPT (0.30) | MAPTSMN1; SMN2 | |
| SCHEMBL23577872 | 0.80 | MAPT (0.30) | MAPT | |
| SCHEMBL23601242 | 0.80 | MAPT (0.41) | MAPTSMN1; SMN2TSHRCSF1REGFR | |
| SCHEMBL23577241 | 0.80 | MAPT (0.43) | MAPTSMN1; SMN2TSHRCSF1REGFR | |
| SCHEMBL23601251 | 0.79 | MAPT (0.35) | MAPTSMN1; SMN2TSHRTP53KDM4E | |
| SCHEMBL23601772 | 0.78 | MAT2A (0.45) | MAPTSMN1; SMN2TSHRCSF1REGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |