Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | C1R | P00736 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30014123 | 0.84 | EGFR (0.39) | NR4A2POLBPDE10ACHKALMNA | |
| SCHEMBL23577130 | 0.84 | EGFR (0.39) | NR4A2POLBPDE10ACHKALMNA | |
| SCHEMBL23576849 | 0.82 | EGFR (0.41) | GAAMAPTKMT2ACHKAKDR | |
| SCHEMBL29909472 | 0.82 | EGFR (0.41) | GAAMAPTKMT2ACHKAKDR | |
| SCHEMBL24721493 | 0.81 | MAPT (0.37) | GAAMAPTADORA1POLBSMN1; SMN2 | |
| SCHEMBL30961048 | 0.80 | GAA (0.50) | GAAMAPTADORA1CHKA | |
| SCHEMBL23577187 | 0.80 | GAA (0.50) | GAAMAPTADORA1CHKA | |
| SCHEMBL23601713 | 0.79 | CHKA (0.39) | GAAMAPTKMT2ANR4A2CHKA | |
| SCHEMBL24807698 | 0.76 | GAA (0.36) | GAAMAPTADORA1KMT2ANR4A2 | |
| SCHEMBL23577932 | 0.76 | GAA (0.36) | GAAMAPTADORA1KMT2ANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |