Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | FERMT2 | Q96AC1 | 2/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29909472 | 0.83 | EGFR (0.41) | CHKAGAAMAPTCSNK2A2CSNK2B | |
| SCHEMBL23576849 | 0.83 | EGFR (0.41) | CHKAGAAMAPTCSNK2A2CSNK2B | |
| SCHEMBL30961048 | 0.81 | GAA (0.50) | CHKAGAAMAPTCSF1R | |
| SCHEMBL23577187 | 0.81 | GAA (0.50) | CHKAGAAMAPTCSF1R | |
| SCHEMBL24807698 | 0.79 | GAA (0.36) | CHKAGAAMAPTNR4A2CSF1R | |
| SCHEMBL23601276 | 0.79 | GAA (0.40) | CHKAGAAMAPTNR4A2LMNA | |
| SCHEMBL29909528 | 0.77 | GAA (0.36) | CHKAGAAMAPTNR4A2LMNA | |
| SCHEMBL23577932 | 0.77 | GAA (0.36) | CHKAGAAMAPTNR4A2LMNA | |
| SCHEMBL23601802 | 0.72 | CSF1R (0.60) | CHKAGAAMAPTCSF1R | |
| SCHEMBL30961034 | 0.72 | CSF1R (0.60) | CHKAGAAMAPTCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |