Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 4/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601321 | 0.86 | EGFR (0.42) | MAT2AEGFRKDRPDGFRB | |
| SCHEMBL29141395 | 0.86 | EGFR (0.42) | MAT2AEGFRKDRPDGFRB | |
| SCHEMBL30146701 | 0.86 | EGFR (0.42) | MAT2AEGFRKDRPDGFRB | |
| SCHEMBL29909408 | 0.86 | IDO1 (0.33) | MAT2APTGES | |
| SCHEMBL23576815 | 0.86 | IDO1 (0.33) | MAT2APTGES | |
| SCHEMBL29210688 | 0.86 | IDO1 (0.33) | MAT2APTGES | |
| SCHEMBL30013536 | 0.86 | IDO1 (0.33) | MAT2APTGES | |
| SCHEMBL23576645 | 0.75 | ESR1 (0.34) | MAT2AEGFRKDRPDGFRB | |
| SCHEMBL30013793 | 0.75 | ESR1 (0.34) | MAT2AEGFRKDRPDGFRB | |
| SCHEMBL23577040 | 0.74 | EGFR (0.43) | EGFRKDRPDGFRBPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |