Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 4/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24721737 | 0.84 | HRH3 (0.50) | HRH3SMN1; SMN2CXCR4CYP2C19CYP2A13 | |
| SCHEMBL11981676 | 0.80 | CXCR4 (0.51) | HRH3SMN1; SMN2CXCR4CYP2C19CYP2A13 | |
| SCHEMBL31002170 | 0.79 | CXCR4 (0.50) | HRH3SMN1; SMN2CXCR4CYP2A13HTT | |
| SCHEMBL27899079 | 0.77 | SMN1; SMN2 (0.60) | HRH3SMN1; SMN2CD274HTTPIK3CA | |
| SCHEMBL1859625 | 0.76 | HRH3 (0.60) | HRH3SMN1; SMN2CXCR4CD274 | |
| SCHEMBL29725198 | 0.76 | CXCR4 (0.50) | HRH3SMN1; SMN2CXCR4CYP2A13 | |
| SCHEMBL16840950 | 0.76 | SMN1; SMN2 (0.51) | HRH3SMN1; SMN2CXCR4PIK3R1PIK3CA | |
| SCHEMBL17807631 | 0.76 | CXCR4 (0.50) | HRH3SMN1; SMN2CXCR4CYP2A13 | |
| SCHEMBL24453628 | 0.75 | ALOX15 (0.48) | HRH3SMN1; SMN2CXCR4CYP2C19CYP2A13 | |
| SCHEMBL11960352 | 0.75 | HRH3 (0.53) | HRH3SMN1; SMN2CXCR4CYP2C19CYP2A13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |