Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP2A13 | Q16696 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11981676 | 0.81 | CXCR4 (0.51) | CXCR4HRH3SMN1; SMN2CYP2A13NPC1 | |
| SCHEMBL17807631 | 0.79 | CXCR4 (0.50) | CXCR4HRH3SMN1; SMN2CYP2A13NPC1 | |
| SCHEMBL21551089 | 0.79 | KDM4E (0.42) | HRH3KDM4EGAA | |
| SCHEMBL29725198 | 0.79 | CXCR4 (0.50) | CXCR4HRH3SMN1; SMN2CYP2A13NPC1 | |
| SCHEMBL16840950 | 0.79 | SMN1; SMN2 (0.51) | CXCR4HRH3SMN1; SMN2NPC1ALOX15 | |
| SCHEMBL29725214 | 0.79 | KDM4E (0.42) | HRH3KDM4EGAA | |
| SCHEMBL23601362 | 0.79 | HRH3 (0.47) | CXCR4HRH3SMN1; SMN2CYP2A13ALOX15 | |
| SCHEMBL110617 | 0.78 | HRH3 (0.53) | CXCR4HRH3SMN1; SMN2CYP2A13NPC1 | |
| SCHEMBL21551028 | 0.77 | NPC1 (0.47) | CXCR4HRH3SMN1; SMN2CYP2A13NPC1 | |
| SCHEMBL29725199 | 0.77 | NPC1 (0.47) | CXCR4HRH3SMN1; SMN2CYP2A13NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4655304-A1 | MACROCYCLIC AMINOPYRIDINE COMPOUNDS AS EGFR INHIBITORS | Yuhan Corporation (KR) | 2025-12-03 | — | — | EP | disclosed |
| WO-2024177362-A1 | MACROCYCLIC AMINOPYRIDINE COMPOUNDS AS EGFR INHIBITORS | YUHAN CORPORATION (KR) | 2024-08-29 | — | — | WO | disclosed |