Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12038285 | 0.90 | MAOA (0.50) | MAOAMAOBCYP1A2CYP2A6TAAR1 | |
| SCHEMBL13510883 | 0.85 | MAOA (0.46) | MAOAMAOBTP53MAPTHRH3 | |
| SCHEMBL28551933 | 0.85 | MAOB (0.46) | MAOAMAOBCYP1A2CYP2A6TAAR1 | |
| SCHEMBL1823450 | 0.79 | MAOB (0.64) | MAOAMAOBTDP1MAPTALDH1A1 | |
| SCHEMBL5644096 | 0.77 | MAOA (0.61) | MAOAMAOBIDO1 | |
| SCHEMBL5349239 | 0.77 | MAOB (0.61) | MAOAMAOBTAAR1AGXTIDO1 | |
| SCHEMBL1821778 | 0.77 | MAOA (0.50) | MAOAMAOBALDH1A1 | |
| SCHEMBL1823270 | 0.77 | MAOA (0.61) | MAOAMAOBTAAR1AGXTIDO1 | |
| SCHEMBL16041470 | 0.77 | MAOA (0.61) | MAOAMAOBCYP2A6TAAR1IDO1 | |
| SCHEMBL1821734 | 0.77 | MAOA (0.61) | MAOAMAOBTAAR1IDO1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |