SCHEMBL5349239

SCHEMBL5349239

NC1(Cc2ccc(F)cc2)CC1

nearest known ligand 0.61

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.61
MAOA P21397 1/20 0.61
LOXL2 Q9Y4K0 1/20 0.46
KDM1A O60341 3/20 0.46
RCOR1 Q9UKL0 3/20 0.46
TAAR1 Q96RJ0 1/20 0.43
IDO1 P14902 4/20 0.41
AGXT P21549 2/20 0.41
SLC6A3 Q01959 1/20 0.38
AOC3 Q16853 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1823777 0.91 MAOA (0.52) MAOBMAOALOXL2KDM1ARCOR1
Hydrochloric Acid SCHEMBL3969767 0.90 MAOB (0.50) MAOBMAOALOXL2KDM1ARCOR1
SCHEMBL1823450 0.79 MAOB (0.64) MAOBMAOALOXL2KDM1A
SCHEMBL2470972 0.78 TAAR1 (0.50) MAOBMAOALOXL2KDM1ARCOR1
SCHEMBL23601588 0.77 MAOA (0.61) MAOBMAOATAAR1IDO1AGXT
SCHEMBL1823510 0.77 MAOA (0.50) MAOBMAOAKDM1ARCOR1IDO1
SCHEMBL1823270 0.77 MAOA (0.61) MAOBMAOAKDM1ARCOR1TAAR1
SCHEMBL16041470 0.77 MAOA (0.61) MAOBMAOAKDM1ARCOR1TAAR1
SCHEMBL5644096 0.77 MAOA (0.61) MAOBMAOAKDM1AIDO1
SCHEMBL1821734 0.77 MAOA (0.61) MAOBMAOATAAR1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3606910-A1 TRIAZOLE COMPOUND AND USE THEREOF IN AGRICULTURE Dongguan Hec Pesticides R&D Co., Ltd. (CN) 2020-02-12 EP disclosed
WO-2018184579-A1 TRIAZOLE COMPOUND AND USE THEREOF IN AGRICULTURE DONGGUAN HEC TECH R&D CO., LTD. (CN) 2018-10-11 WO disclosed
US-20120053165-A1 Novel Phenyl Imidazoles and Phenyl Triazoles As Gamma-Secretase Modulators PFIZER INC. (US) 2012-03-01 US disclosed
US-20120053165-A1 Novel Phenyl Imidazoles and Phenyl Triazoles As Gamma-Secretase Modulators PFIZER INC. (US) 2012-03-01 US disclosed
WO-2010100606-A1 NOVEL PHENYL IMIDAZOLES AND PHENYL TRIAZOLES AS GAMMA-SECRETASE MODULATORS PFIZER INC. (US) 2010-09-10 WO disclosed
US-7217723-B2 Substituted benzothiophenes, e.g., 7Z)-7-hydroxyimino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-sulfonic acid [2-(4-fluorophenyl)-2-hydroxyethyl]-methyl-amide; treating allergies such as atopic dermatitis, allergic coryza, bronchial asthma, hypersensitive pneumoniac and pulmonary aspergillosis. EISAI CO., LTD. (JP) 2007-05-15 US disclosed
US-20050227959-A1 Heterocyclic compound having oxime group EISAI CO., LTD. (JP) 2005-10-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120053165-A1 Novel Phenyl Imidazoles and Phenyl Triazoles As Gamma-Secretase Modulators BACE1, BACE2, PSEN1 MAOB 1367/4885MAOA 1573/4885LOXL2 4378/4885
US-20050227959-A1 Heterocyclic compound having oxime group STAT6, HRH4, HRH2 MAOB 913/4885MAOA 1201/4885LOXL2 1145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.