Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.59 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.49 |
| ▸ | CTSA | P10619 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | BCR | P11274 | 2/20 | 0.41 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13025 | 0.91 | PDPK1 (0.60) | PDPK1LOXL2ADRB2CYP2A6CTSA | |
| SCHEMBL5147639 | 0.80 | PDPK1 (0.91) | PDPK1LOXL2ADRB2CYP2A6KDR | |
| SCHEMBL558643 | 0.80 | PDPK1 (0.63) | PDPK1LOXL2ADRB2CYP2A6ALDH1A1 | |
| SCHEMBL24721069 | 0.80 | PDPK1 (0.54) | PDPK1LOXL2ADRB2CYP2A6CTSA | |
| SCHEMBL14777142 | 0.79 | CTSA (0.42) | PDPK1LOXL2ADRB2CYP2A6CTSA | |
| SCHEMBL4425765 | 0.79 | PDPK1 (0.74) | PDPK1LOXL2ADRB2CYP2A6CTSA | |
| SCHEMBL16159287 | 0.78 | PDPK1 (0.67) | PDPK1LOXL2ADRB2CYP2A6KDR | |
| Water SCHEMBL20550178 | 0.78 | ADRB2 (0.62) | PDPK1LOXL2ADRB2CYP2A6ALDH1A1 | |
| SCHEMBL15805858 | 0.78 | PDPK1 (0.72) | PDPK1LOXL2ADRB2CYP2A6KDR | |
| SCHEMBL17704291 | 0.78 | PDPK1 (0.65) | PDPK1LOXL2ADRB2CYP2A6KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |