Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 4/20 | 0.57 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ME2 | P23368 | 7/20 | 0.50 |
| ▸ | ME1 | P48163 | 7/20 | 0.50 |
| ▸ | ME3 | Q16798 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26502460 | 0.86 | PARP1 (0.59) | SMOPANK3PARP1KDM4ESMN1; SMN2 | |
| SCHEMBL23972265 | 0.85 | ME2 (0.57) | SMOPANK3PARP1KDM4ESMN1; SMN2 | |
| SCHEMBL27723056 | 0.84 | PANK3 (0.59) | PANK3PARP1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL5237033 | 0.83 | PANK3 (0.57) | PANK3PARP1KDM4ESMN1; SMN2ME2 | |
| SCHEMBL1630859 | 0.83 | L3MBTL1 (0.58) | SMOPANK3PARP1KDM4ESMN1; SMN2 | |
| SCHEMBL23972257 | 0.82 | ME2 (0.75) | PANK3PARP1KDM4ESMN1; SMN2ME2 | |
| SCHEMBL26296502 | 0.82 | PARP1 (0.53) | SMOPANK3PARP1KDM4ESMN1; SMN2 | |
| SCHEMBL14269363 | 0.82 | PANK3 (0.56) | PANK3PARP1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL23600944 | 0.82 | PANK3 (0.58) | SMOPANK3ME2ME1ME3 | |
| SCHEMBL8291757 | 0.81 | SMN1; SMN2 (0.70) | SMOPANK3KDM4ESMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |