Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601644 | 0.93 | TP53 (0.31) | TP53MAPT | |
| SCHEMBL23601381 | 0.87 | — | — | |
| SCHEMBL23601865 | 0.83 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL23601986 | 0.83 | SMN1; SMN2 (0.32) | SMN1; SMN2TP53MAPT | |
| SCHEMBL31169409 | 0.79 | — | — | |
| SCHEMBL24721444 | 0.79 | — | — | |
| SCHEMBL23601004 | 0.78 | MAT2A (0.36) | SMN1; SMN2TP53MAPTPOLB | |
| SCHEMBL23576693 | 0.78 | MAT2A (0.35) | SMN1; SMN2 | |
| SCHEMBL29909100 | 0.78 | MAT2A (0.35) | SMN1; SMN2 | |
| SCHEMBL23577133 | 0.77 | PRMT5 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |