Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601353 | 0.91 | KMT2A (0.38) | MEN1KMT2ASMN1; SMN2HRH4MAPT | |
| SCHEMBL23576693 | 0.88 | MAT2A (0.35) | MAT2AMEN1KMT2ASMN1; SMN2HRH4 | |
| SCHEMBL29909100 | 0.88 | MAT2A (0.35) | MAT2AMEN1KMT2ASMN1; SMN2HRH4 | |
| SCHEMBL23601241 | 0.88 | SMN1; SMN2 (0.35) | MAT2AMEN1KMT2ASMN1; SMN2HRH4 | |
| SCHEMBL23601909 | 0.86 | MAT2A (0.33) | MAT2AMEN1KMT2ASMN1; SMN2HRH4 | |
| SCHEMBL23601650 | 0.85 | MAPT (0.31) | MEN1KMT2ASMN1; SMN2MAPTPOLB | |
| SCHEMBL23601772 | 0.85 | MAT2A (0.45) | MAT2AKMT2ASMN1; SMN2MAPTPRMT5 | |
| SCHEMBL23601586 | 0.84 | SMN1; SMN2 (0.35) | MAT2AMEN1KMT2ASMN1; SMN2HRH4 | |
| SCHEMBL23601458 | 0.84 | MAT2A (0.36) | MAT2ASMN1; SMN2HRH4MAPTPRMT5 | |
| SCHEMBL23601007 | 0.84 | MAPT (0.36) | MEN1KMT2ASMN1; SMN2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |