Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CSF1R | P07333 | 4/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29909135 | 0.89 | MAT2A (0.37) | MAT2AMAPTEGFRSMN1; SMN2TP53 | |
| SCHEMBL23577190 | 0.89 | MAT2A (0.37) | MAT2AMAPTEGFRSMN1; SMN2TP53 | |
| SCHEMBL30961036 | 0.89 | CSF1R (0.44) | MAT2AMAPTCSF1RTP53PRMT5 | |
| SCHEMBL23577499 | 0.89 | CSF1R (0.44) | MAT2AMAPTCSF1RTP53PRMT5 | |
| SCHEMBL23577196 | 0.88 | PDGFRB (0.38) | MAT2AEGFRKDM4EALDH1A1HPGD | |
| SCHEMBL29909162 | 0.88 | PDGFRB (0.38) | MAT2AEGFRKDM4EALDH1A1HPGD | |
| SCHEMBL30920925 | 0.87 | TP53 (0.39) | MAT2AMAPTCSF1RTP53PRMT5 | |
| SCHEMBL23601235 | 0.87 | FNTA (0.40) | MAT2AMAPTSMN1; SMN2TP53KDM4E | |
| SCHEMBL29909768 | 0.87 | FNTA (0.40) | MAT2AMAPTSMN1; SMN2TP53KDM4E | |
| SCHEMBL23576919 | 0.87 | FNTA (0.38) | MAT2AMAPTEGFRSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |