Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 5/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577190 | 1.00 | MAT2A (0.37) | MAT2AFNTAFNTBMAPTSMN1; SMN2 | |
| SCHEMBL29909768 | 0.95 | FNTA (0.40) | MAT2AFNTAFNTBMAPTSMN1; SMN2 | |
| SCHEMBL23601235 | 0.95 | FNTA (0.40) | MAT2AFNTAFNTBMAPTSMN1; SMN2 | |
| SCHEMBL30920925 | 0.93 | TP53 (0.39) | MAT2AFNTAFNTBMAPTTP53 | |
| SCHEMBL23576935 | 0.90 | FNTA (0.36) | MAT2AFNTAFNTBMAPTTP53 | |
| SCHEMBL23577059 | 0.89 | FNTA (0.41) | MAT2AFNTAFNTBMAPTTP53 | |
| SCHEMBL29909398 | 0.89 | TP53 (0.37) | FNTAFNTBMAPTTP53ALDH1A1 | |
| SCHEMBL23600785 | 0.89 | TP53 (0.37) | FNTAFNTBMAPTTP53ALDH1A1 | |
| SCHEMBL29909922 | 0.89 | FNTA (0.41) | MAT2AFNTAFNTBMAPTTP53 | |
| SCHEMBL23601772 | 0.89 | MAT2A (0.45) | MAT2AFNTAFNTBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |