SCHEMBL23601901

SCHEMBL23601901

C/C(=C\c1cc(F)cc(N(C)c2nc3nncn3c3cc(Cl)ccc23)c1)C(C)(C)C1CC1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAT2A P31153 1/20 0.32
HRH4 Q9H3N8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23577577 0.80 MAT2A (0.32) MAT2AHRH4
SCHEMBL24721449 0.78 MAT2A (0.31) MAT2A
SCHEMBL23601004 0.78 MAT2A (0.36) MAT2AHRH4
SCHEMBL23601862 0.78 FNTA (0.32)
SCHEMBL23601647 0.77 TNIK (0.31) MAT2A
SCHEMBL23601775 0.77 MAT2A (0.31) MAT2AHRH4
SCHEMBL29909100 0.77 MAT2A (0.35) MAT2AHRH4
SCHEMBL23576693 0.77 MAT2A (0.35) MAT2AHRH4
SCHEMBL23601909 0.77 MAT2A (0.33) MAT2AHRH4
SCHEMBL23577545 0.76 MAT2A (0.34) MAT2AHRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021130638-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS CARNA BIOSCIENCES, INC. (JP) 2021-07-01 WO disclosed