SCHEMBL23601927

SCHEMBL23601927

c1ccc(-c2ccc3c(c2)oc2cc(-c4nc(-c5ccccc5)nc(-n5c6ccccc6c6ccc7c8ccccc8n(-c8ccccc8)c7c65)n4)ccc23)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.38
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
MMP12 P39900 1/20 0.32
MMP13 P45452 1/20 0.32
PRKDC P78527 1/20 0.32
AVPR1A P37288 1/20 0.32
KMT2A Q03164 4/20 0.32
IL1R1 P14778 1/20 0.32
PGR P06401 1/20 0.32
ABCG2 Q9UNQ0 2/20 0.31
MEN1 O00255 3/20 0.31
ALDH1A1 P00352 3/20 0.31
MAPT P10636 2/20 0.31
HTT P42858 1/20 0.31
PTGER4 P35408 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31
HCRTR1 O43613 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25965244 0.98 KDM4E (0.36) L3MBTL1KDM4EATMMMP12MMP13
SCHEMBL27070305 0.98 ATM (0.36) L3MBTL1KDM4EATMMMP12MMP13
SCHEMBL24390342 0.98 ATM (0.35) L3MBTL1KDM4EATMMMP12MMP13
SCHEMBL22049203 0.97 KDM4E (0.37) L3MBTL1KDM4EATMMMP12MMP13
SCHEMBL22049198 0.97 KDM4E (0.37) L3MBTL1KDM4EATMMMP12MMP13
SCHEMBL25965049 0.96 L3MBTL1 (0.35) L3MBTL1KDM4EATMMMP12MMP13
SCHEMBL24716540 0.96 ATM (0.35) L3MBTL1KDM4EATMMMP12MMP13
SCHEMBL24390326 0.96 KDM4E (0.33) L3MBTL1KDM4EATMMMP12MMP13
SCHEMBL19769766 0.95 KDM4E (0.38) L3MBTL1KDM4EATMMMP12MMP13
SCHEMBL25965077 0.95 L3MBTL1 (0.40) L3MBTL1KDM4EATMMMP12MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230284526-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-09-07 US disclosed
US-20230284526-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-09-07 US disclosed
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 US disclosed
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 US disclosed
US-20230131577-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-04-27 US disclosed
US-20230131577-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-04-27 US disclosed
US-20220416177-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR MANUFACTURING SAME NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2022-12-29 US disclosed
WO-2021131755-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR MANUFACTURING SAME 日鉄ケミカル&マテリアル株式会社 2021-07-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230131577-A1 ORGANIC ELECTROLUMINESCENT ELEMENT LEF1, EPB41, EPB41L2 L3MBTL1 877/4885KDM4E 1097/4885ATM 3975/4885
US-20220416177-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR MANUFACTURING SAME NR4A3, NR4A1, NR4A2 L3MBTL1 532/4885KDM4E 594/4885ATM 4358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.