Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8507957 | 0.84 | KDM4E (0.57) | SMN1; SMN2KDM4EDNM1CHRM2ALDH1A1 | |
| SCHEMBL2361301 | 0.84 | ENPEP (0.42) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL8508004 | 0.81 | KDM4E (0.56) | SMN1; SMN2KDM4EDNM1CHRM2ALDH1A1 | |
| SCHEMBL7105832 | 0.79 | KDM4E (0.54) | SMN1; SMN2KDM4EDNM1CHRM2ALDH1A1 | |
| SCHEMBL2361200 | 0.79 | CYP2D6 (0.50) | SMN1; SMN2ALDH1A1NPC1RAB9AGAA | |
| SCHEMBL27597841 | 0.78 | CHRM2 (0.69) | SMN1; SMN2KDM4ECHRM2ALDH1A1HPGD | |
| SCHEMBL15208597 | 0.78 | KDM4E (0.60) | SMN1; SMN2KDM4EDNM1CHRM2ALDH1A1 | |
| SCHEMBL15208596 | 0.78 | KDM4E (0.60) | SMN1; SMN2KDM4EDNM1CHRM2ALDH1A1 | |
| SCHEMBL4928781 | 0.77 | CHRM2 (0.71) | SMN1; SMN2KDM4ECHRM2ALDH1A1HPGD | |
| SCHEMBL4016034 | 0.76 | SMN1; SMN2 (0.61) | SMN1; SMN2KDM4ECHRM2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011095218-A1 | TEMPLATE-FIXED PEP TIDOMIME TICS WITH CXCR7 MODULATING ACTIVITY | POLYPHOR AG (CH) | 2011-08-11 | — | — | WO | disclosed |