Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPEP | Q07075 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.34 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2360199 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL15208850 | 0.75 | GRIN3B (0.46) | — | |
| SCHEMBL15208845 | 0.75 | GRIN3B (0.46) | — | |
| SCHEMBL2361200 | 0.75 | CYP2D6 (0.50) | ENPEPSMN1; SMN2ALDH1A1 | |
| SCHEMBL19214748 | 0.72 | EGLN2 (0.42) | SMN1; SMN2ALDH1A1SHMT2 | |
| SCHEMBL2238009 | 0.71 | ARG1 (0.43) | — | |
| SCHEMBL2238003 | 0.71 | ARG1 (0.43) | — | |
| SCHEMBL2329796 | 0.70 | ARG1 (0.39) | ALDH1A1LTA4H | |
| SCHEMBL2236602 | 0.70 | ARG1 (0.39) | ALDH1A1LTA4H | |
| SCHEMBL2234954 | 0.70 | ENPEP (0.40) | ENPEPSMN1; SMN2ALDH1A1TBXAS1SHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011095218-A1 | TEMPLATE-FIXED PEP TIDOMIME TICS WITH CXCR7 MODULATING ACTIVITY | POLYPHOR AG (CH) | 2011-08-11 | — | — | WO | disclosed |