Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.59 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.58 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30464883 | 0.91 | PPARA (0.72) | PPARAPTGS1NPC1RAB9AALDH1A1 | |
| SCHEMBL7359872 | 0.91 | PPARA (0.72) | PPARAPTGS1NPC1RAB9AALDH1A1 | |
| SCHEMBL3675332 | 0.90 | PPARA (0.57) | PPARAPTGDRPTGDR2PTGS1NPC1 | |
| SCHEMBL2359864 | 0.83 | PTGS1 (0.56) | PPARAPTGS1NPC1RAB9AALDH1A1 | |
| Pentachlorophenol SCHEMBL7355120 | 0.82 | PPARA (0.61) | PPARAPTGDRPTGDR2PTGS1NPC1 | |
| SCHEMBL7822082 | 0.80 | PPARA (0.58) | PPARAPTGS1NPC1RAB9AALDH1A1 | |
| SCHEMBL5830687 | 0.78 | ALOX15 (0.55) | PTGDRPTGDR2ALDH1A1PPARGPPARD | |
| SCHEMBL14093024 | 0.78 | PTGDR2 (0.58) | PTGDR2SMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL4327196 | 0.78 | ALDH1A1 (0.65) | PPARAPTGS1NPC1RAB9AALDH1A1 | |
| SCHEMBL4327190 | 0.77 | PPARA (0.85) | PPARAPTGS1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8703692-B2 | 7-(alk-1′enyl)-2H-benzo[B][1,4]dioxepin-3(4H)-ones and their use in fragrance applications | GIVAUDAN SA (CH) | 2014-04-22 | — | — | US | disclosed |
| EP-2534143-A1 | 7 - (ALK- 1 ' -ENYL) - 2H-BENZO [B][1, 4]DIOXEPIN- 3 (4H) - ONES AND THEIR USE IN FRAGRANCE APPLICATIONS | Givaudan SA (CH) | 2012-12-19 | — | — | EP | disclosed |
| US-20120309670-A1 | 7-(ALK-1'-ENYL)-2H-BENZO[B][1,4]DIOXEPIN-3(4H)-ONES AND THEIR USE IN FRAGRANCE APPLICATIONS | GIVAUDAN SA (CH) | 2012-12-06 | — | — | US | disclosed |
| WO-2011098472-A1 | 7 - (ALK- 1 ' -ENYL) - 2H-BENZO [B] [1, 4] DIOXEPIN- 3 (4H) - ONES AND THEIR USE IN FRAGRANCE APPLICATIONS | GIVAUDAN SA (CH) | 2011-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309670-A1 | 7-(ALK-1'-ENYL)-2H-BENZO[B][1,4]DIOXEPIN-3(4H)-ONES AND THEIR USE IN FRAGRANCE APPLICATIONS | ALK, OR51E2, ALKBH3 | PPARA 3082/4885PTGDR 862/4885PTGDR2 949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.