SCHEMBL236067

SCHEMBL236067

N=C(N)NCCC[C@H](NC(=O)CNC(=O)[C@@H](CCCNC(=N)N)NC(=O)OCc1ccccc1)C(=O)Nc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.51

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SIRT5 Q9NXA8 5/20 0.51
SIRT2 Q8IXJ6 13/20 0.51
SIRT1 Q96EB6 12/20 0.51
SIRT3 Q9NTG7 3/20 0.49
TGM2 P21980 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14286269 1.00 SIRT5 (0.51) SIRT5SIRT2SIRT1SIRT3TGM2
SCHEMBL14264834 1.00 SIRT5 (0.51) SIRT5SIRT2SIRT1SIRT3TGM2
Hydrochloric Acid SCHEMBL3503087 0.99 SIRT5 (0.51) SIRT5SIRT2SIRT1SIRT3TGM2
SCHEMBL2268022 0.94 SIRT5 (0.57) SIRT5SIRT2SIRT1SIRT3TGM2
Hydrochloric Acid SCHEMBL10884941 0.94 SIRT5 (0.56) SIRT5SIRT2SIRT1SIRT3TGM2
Hydrochloric Acid SCHEMBL10943848 0.94 SIRT5 (0.56) SIRT5SIRT2SIRT1SIRT3TGM2
SCHEMBL17289476 0.93 SIRT5 (0.55) SIRT5SIRT2SIRT1SIRT3TGM2
SCHEMBL1529286 0.93 SIRT2 (0.48) SIRT5SIRT2SIRT1SIRT3
Acetic Acid SCHEMBL8862727 0.91 SIRT2 (0.46) SIRT5SIRT2SIRT1SIRT3
SCHEMBL9763743 0.91 ALDH1A1 (0.48) SIRT5SIRT2SIRT1SIRT3TGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 464 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119842867-A Stable rivaroxaban content detection kit with strong anti-interference capability 北京九强生物技术股份有限公司 2025-04-18 CN claimed
CN-115290581-A anti-Xa assay kit (chromogenic substrate method) 上海太阳生物技术有限公司 2022-11-04 CN claimed
US-20250179523-A1 METHODS FOR THE PURIFICATION OF VIRAL VECTORS OSPEDALE SAN RAFFAELE S.R.L. (IT) 2025-06-05 US disclosed
CN-119842867-A Stable rivaroxaban content detection kit with strong anti-interference capability 北京九强生物技术股份有限公司 2025-04-18 CN disclosed
US-12173307-B2 Methods for the purification of viral vectors BIOVERATIV THERAPEUTICS INC. (US) 2024-12-24 US disclosed
CN-118221785-A Novel AAV variants 上海药明康德新药开发有限公司 2024-06-21 CN disclosed
CN-113518824-B Novel AAV variants 上海药明康德新药开发有限公司 2024-02-23 CN disclosed
CN-114207196-B Novel AAV libraries 上海药明康德新药开发有限公司 2024-01-26 CN disclosed
CN-117106856-A anti-Xa activity assay kit and preparation method thereof 武汉塞力斯生物技术有限公司 2023-11-24 CN disclosed
CN-115290581-B Anti-Xa assay kit and method for detecting anti-Xa activity 上海太阳生物技术有限公司 2023-10-13 CN disclosed
EP-4171657-A1 METHODS FOR THE REMOVAL OF FREE FACTOR VIII FROM PREPARATIONS OF LENTIVIRAL VECTORS MODIFIED TO EXPRESS SAID PROTEIN Bioverativ Therapeutics Inc. (US) 2023-05-03 EP disclosed
EP-0672659-A1 Antithrombotic agents ELI LILLY AND COMPANY (US) 1995-09-20 EP disclosed
EP-0671390-A2 Antithrombotic agents ELI LILLY AND COMPANY (US) 1995-09-13 EP disclosed
WO-1995023608-A1 ANTITHROMBOTIC AGENTS ELI LILLY AND COMPANY (US) 1995-09-08 WO disclosed
WO-1995023609-A1 ANTITHROMBOTIC AGENTS ELI LILLY AND COMPANY (US) 1995-09-08 WO disclosed
EP-0670310-A1 Bisulfite adducts of arginine aldehydes useful as thrombin inhibitors and as anticoagulants ELI LILLY AND COMPANY (US) 1995-09-06 EP disclosed
US-5441965-A Administering a substituted benzothiophene compound ELI LILLY AND COMPANY (US) 1995-08-15 US disclosed
US-5439888-A Antithrombotic agents ELI LILLY AND COMPANY (US) 1995-08-08 US disclosed
EP-0664126-A1 Inhibition of thrombin ELI LILLY AND COMPANY (US) 1995-07-26 EP disclosed
US-5436229-A Di- and tripeptides as anticoagulants ELI LILLY AND COMPANY (US) 1995-07-25 US disclosed