Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27005541 | 0.88 | SLC6A5 (0.47) | SLC6A5EPHX1GNAI3GNAO1GNAI1 | |
| SCHEMBL19988365 | 0.87 | EPHX1 (0.43) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL24238536 | 0.87 | EPHX1 (0.43) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL20863007 | 0.86 | SLC6A5 (0.54) | SLC6A5EPHX1GNAI3GNAO1GNAI1 | |
| SCHEMBL22099464 | 0.86 | SLC6A5 (0.54) | SLC6A5EPHX1GNAI3GNAO1GNAI1 | |
| SCHEMBL26019380 | 0.86 | SLC6A5 (0.54) | SLC6A5EPHX1GNAI3GNAO1GNAI1 | |
| SCHEMBL21076334 | 0.83 | EPHX1 (0.50) | EPHX1DNM1 | |
| SCHEMBL22447142 | 0.83 | EPHX1 (0.50) | EPHX1DNM1 | |
| SCHEMBL19176981 | 0.83 | EPHX1 (0.50) | EPHX1DNM1 | |
| SCHEMBL19336122 | 0.83 | EPHX1 (0.50) | EPHX1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133839-A1 | METHODS OF PREPARING N6-((2-AZIDOETHOXY)CARBONYL)LYSINE | Synthorx, Inc. (US) | 2021-07-01 | — | — | WO | disclosed |