Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 11/20 | 0.53 |
| ▸ | DGAT1 | O75907 | 6/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.52 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4469809 | 0.88 | KDM4E (0.64) | NPBWR1DGAT1KCNH2SOAT1KDM4E | |
| SCHEMBL6325961 | 0.86 | NPBWR1 (0.59) | NPBWR1DGAT1KCNH2SOAT1KDM4E | |
| SCHEMBL30343717 | 0.86 | NPBWR1 (0.59) | NPBWR1DGAT1KCNH2SOAT1KDM4E | |
| SCHEMBL15245140 | 0.84 | DGAT1 (0.67) | NPBWR1DGAT1KCNH2SOAT1 | |
| SCHEMBL21705325 | 0.80 | HDAC6 (0.64) | NPBWR1DGAT1KCNH2SOAT1 | |
| SCHEMBL10326035 | 0.80 | NPBWR1 (0.58) | NPBWR1DGAT1KCNH2SOAT1 | |
| SCHEMBL31027889 | 0.80 | HDAC6 (0.64) | NPBWR1DGAT1KCNH2SOAT1 | |
| SCHEMBL10325105 | 0.80 | NPBWR1 (0.58) | NPBWR1DGAT1KCNH2SOAT1 | |
| SCHEMBL15245160 | 0.80 | DGAT1 (0.79) | NPBWR1DGAT1KCNH2SOAT1NPC1 | |
| SCHEMBL31289472 | 0.80 | MEN1 (0.58) | NPBWR1DGAT1KCNH2SOAT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099832-A2 | NOVEL BENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CRYSTALGENOMICS, INC. (KR) | 2011-08-18 | — | — | WO | disclosed |