Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Sulfide SCHEMBL5999599 | 0.98 | DNM1 (0.52) | DNM1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL991989 | 0.98 | DNM1 (0.52) | DNM1MEN1KMT2ATP53MAPK1 | |
| Hydrochloric Acid SCHEMBL28683171 | 0.95 | DNM1 (0.50) | DNM1MEN1KMT2ATP53MAPK1 | |
| Water SCHEMBL235918 | 0.95 | DNM1 (0.50) | DNM1MEN1KMT2ATP53MAPK1 | |
| Bromide SCHEMBL28192738 | 0.95 | DNM1 (0.50) | DNM1MEN1KMT2ATP53MAPK1 | |
| Hydrogen Sulfide SCHEMBL5999597 | 0.95 | DNM1 (0.50) | DNM1MEN1KMT2ATP53MAPK1 | |
| Hydrochloric Acid SCHEMBL239800 | 0.95 | KDM4E (0.54) | DNM1MEN1KMT2ATP53MAPK1 | |
| Iodide SCHEMBL5084920 | 0.95 | DNM1 (0.50) | DNM1MEN1KMT2ATP53MAPK1 | |
| Fluoride Ion SCHEMBL27681009 | 0.95 | DNM1 (0.50) | DNM1MEN1KMT2ATP53MAPK1 | |
| Iodide SCHEMBL5092951 | 0.95 | DNM1 (0.50) | DNM1MEN1KMT2ATP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084683-A | Blue light-emitting lead-based halide, and preparation method and application thereof | 南方科技大学 | 2024-05-28 | — | — | CN | claimed |
| CN-108148394-B | Storage-stable one-component polyurethane prepregs from polyurethane compositions and moldings produced therefrom | 赢创运营有限公司 | 2021-12-28 | — | — | CN | claimed |
| EP-3330311-B1 | STORAGE STABLE 1K-POLYURETHANE-PREPREGS AND MOULDED ARTICLE MADE FROM SAME ON THE BASIS OF A POLYURETHANE COMPOSITION | EVONIK OPERATIONS GMBH (DE) | 2021-05-05 | — | — | EP | claimed |
| US-10633519-B2 | Storage-stable polyurethane prepregs and mouldings produced therefrom composed of a polyurethane composition with liquid resin components | EVONIK OPERATIONS GMBH (DE) | 2020-04-28 | — | — | US | claimed |
| US-10626236-B2 | Storage-stable one-component polyurethane prepregs and shaped bodies composed of polyurethane composition that have been produced therefrom | EVONIK OPERATIONS GMBH (DE) | 2020-04-21 | — | — | US | claimed |
| CN-108148394-A | The stable mono-component polyurethane prepreg of storage from urethane composition and thus obtained formed body | 赢创德固赛有限公司 | 2018-06-12 | — | — | CN | claimed |
| US-20180155515-A1 | STORAGE-STABLE ONE-COMPONENT POLYURETHANE PREPREGS AND SHAPED BODIES COMPOSED OF POLYURETHANE COMPOSITION THAT HAVE BEEN PRODUCED THEREFROM | EVONIK OPERATIONS GMBH (DE) | 2018-06-07 | — | — | US | claimed |
| EP-3330311-A1 | STORAGE STABLE 1K-POLYURETHANE-PREPREGS AND MOULDED ARTICLE MADE FROM SAME ON THE BASIS OF A POLYURETHANE COMPOSITION | Evonik Degussa GmbH (DE) | 2018-06-06 | — | — | EP | claimed |
| CN-103459452-B | Storage-stable polyurethane prepregs made of polyurethane compositions with liquid resin components and molded parts made therefrom | EVONIK DEGUSSA GMBH (DE) | 2016-11-30 | — | — | CN | claimed |
| EP-2411439-B1 | PREPEGS AND MOLDED BODIES PRODUCED THEREOF AT LOW TEMPERATURE | EVONIK DEGUSSA GMBH (DE) | 2016-11-16 | — | — | EP | claimed |
| EP-2188320-A1 | DUAL CURE FORMULATIONS WITH COMPONENTS COMPRISING URETDIONE GROUPS | Evonik Degussa GmbH (DE) | 2010-05-26 | — | — | EP | claimed |
| EP-2185616-A1 | REACTIVE ISOCYANATE COMPOSITIONS | Evonik Degussa GmbH (DE) | 2010-05-19 | — | — | EP | claimed |
| CN-100532367-C | High stack-density sheet structural melamine cyanurate and production method and application for flame-resistant material | HANGZHOU JLS FLAME RETARDANTS (CN) | 2009-08-26 | — | — | CN | claimed |
| WO-2009080479-A1 | REACTIVE ISOCYANATE COMPOSITIONS | EVONIK DEGUSSA GMBH (DE) | 2009-07-02 | — | — | WO | claimed |
| WO-2009077222-A1 | DUAL CURE FORMULATIONS WITH COMPONENTS COMPRISING URETDIONE GROUPS | EVONIK DEGUSSA GMBH (DE) | 2009-06-25 | — | — | WO | claimed |
| WO-2008138855-A1 | POLYURETHANE COMPOSITIONS CURABLE AT LOW TEMPERATURE, HAVING URETDIONE GROUPS AND COMPRISING POLYMERS BASED ON SECONDARY POLYOLS CARRYING OH-GROUPS | EVONIK DEGUSSA GMBH (DE) | 2008-11-20 | — | — | WO | claimed |
| US-20080265201-A1 | LOW-TEMPERATURE-CURABLE POLYURETHANE COMPOSITIONS WITH URETDIONE GROUPS, CONTAINING POLYMERS BASED ON POLYOLS THAT CARRY SECONDARY OH GROUPS | DEGUSSA GMBH (DE) | 2008-10-30 | — | — | US | claimed |
| CN-101293950-A | Low-temperature-curable polyurethane compositions with uretdione groups, containing polymers based on polyols that carry secondary oh groups | DEGUSSA (DE) | 2008-10-29 | — | — | CN | claimed |
| WO-2008028769-A1 | LOW-TEMPERATURE-CURABLE POLYURETHANE COMPOSITIONS CONTAINING URETDIONE GROUPS AND WITH QUATERNARY AMMONIUM HALIDES | EVONIK DEGUSSA GMBH (DE) | 2008-03-13 | — | — | WO | claimed |
| CN-101037417-A | High stack-density sheet structural melamine cyanurate and production method and application for flame-resistant material | HANGZHOU JLS FLAME RETARDANTS (CN) | 2007-09-19 | — | — | CN | claimed |