Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Sulfide SCHEMBL5999599 | 0.98 | DNM1 (0.52) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL991989 | 0.98 | DNM1 (0.52) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| Fluoride Ion SCHEMBL27681009 | 0.95 | DNM1 (0.50) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28683171 | 0.95 | DNM1 (0.50) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| Bromide SCHEMBL28192738 | 0.95 | DNM1 (0.50) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5092394 | 0.95 | KDM4E (0.54) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| Hydrogen Sulfide SCHEMBL5999597 | 0.95 | DNM1 (0.50) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| Iodide SCHEMBL236084 | 0.95 | DNM1 (0.50) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5085030 | 0.95 | KDM4E (0.54) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| Water SCHEMBL235918 | 0.95 | DNM1 (0.50) | KDM4EALDH1A1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 706 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3718629-B1 | MODIFIED Y-TYPE MOLECULAR SIEVE AND PREPARATION METHOD THEREFOR, HYDROCRACKING CATALYST AND PREPARATION METHOD THEREFOR, AND METHOD FOR HYDROCRACKING HYDROCARBON OIL | CHINA PETROLEUM & CHEM CORP (CN) | 2026-04-01 | — | — | EP | claimed |
| US-12331458-B2 | Method for decolorizing polyester fabric and polyester fabric | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2025-06-17 | — | — | US | claimed |
| CN-120118320-A | Polyester-based multi-block thermotropic shape memory material with adjustable performance and preparation method thereof | 大连理工大学 | 2025-06-10 | — | — | CN | claimed |
| CN-119898789-A | Flower-like sphere mordenite as well as preparation method and application thereof | 中国石油化工股份有限公司 | 2025-04-29 | — | — | CN | claimed |
| US-12257567-B2 | Process for preparation of superabsorbent polymer | UPL LTD (IN) | 2025-03-25 | — | — | US | claimed |
| CN-119555859-A | High-sensitivity high-flux identification method for saccharide compounds based on chlorine enhanced ionization | 北京大学 | 2025-03-04 | — | — | CN | claimed |
| CN-119506974-A | Method for recovering tungsten carbide and cobalt from waste tungsten-cobalt hard alloy | 赣州有色冶金研究所有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-117769588-B | Methods and reagents for enhancing chemiluminescent signals | 欧蒙医学实验诊断股份公司 | 2025-02-21 | — | — | CN | claimed |
| CN-119431409-A | Bipyridine coordinated catalyst, preparation method, composite catalyst and application | 上海元革新材料科技有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-119143628-A | Four-center Schiff base metal compound and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2024-12-17 | — | — | CN | claimed |
| CN-101293950-A | Low-temperature-curable polyurethane compositions with uretdione groups, containing polymers based on polyols that carry secondary oh groups | DEGUSSA (DE) | 2008-10-29 | — | — | CN | claimed |
| CN-101195717-A | Organic surface modifying method of attapulgite | NANDA ZIJIN SCIENCE AND TECHNO (CN) | 2008-06-11 | — | — | CN | claimed |
| CN-100384909-C | Polycarbonate material in alternating structure | UNIV DALIAN SCIENCE & ENG (CN) | 2008-04-30 | — | — | CN | claimed |
| CN-101037417-A | High stack-density sheet structural melamine cyanurate and production method and application for flame-resistant material | HANGZHOU JLS FLAME RETARDANTS (CN) | 2007-09-19 | — | — | CN | claimed |
| CN-100334130-C | Preparation process of polyester carbonate with high molecular weight whole alternant structure | UNIV DALIAN SCIENCE & ENG (CN) | 2007-08-29 | — | — | CN | claimed |
| CN-1887934-A | Polycarbonate material in alternating structure | UNIV DALIAN SCIENCE & ENG (CN) | 2007-01-03 | — | — | CN | claimed |
| CN-1560111-A | Preparation process of polyester carbonate with high molecular weight whole alternant structure | 大连理工大学 | 2005-01-05 | — | — | CN | claimed |
| EP-0249556-B1 | PROCESS FOR THE PREPARATION OF ALPHA-HALOGENATED ORGANIC ESTERS OF CARBONIC ACID | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1990-08-29 | — | — | EP | claimed |
| US-4782190-A | Process for the preparation of 4-nitrophenetol | BAYER AKTIENGESELLSCHAFT (DE) | 1988-11-01 | — | — | US | claimed |
| US-4012428-A | Method for preparing 3-methyl-2-(4-halogenophenyl)-butyronitrile | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-03-15 | — | — | US | claimed |