Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK1 | P51617 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30405860 | 0.90 | CYP2D6 (0.33) | LRRK2 | |
| SCHEMBL23608952 | 0.88 | PDE5A (0.36) | BACE1BACE2PDE10A | |
| SCHEMBL23609131 | 0.88 | MAPK8 (0.30) | — | |
| SCHEMBL23608969 | 0.72 | SMN1; SMN2 (0.40) | IRAK1NPY5R | |
| SCHEMBL23608955 | 0.71 | IRAK4 (0.33) | BACE1BACE2 | |
| SCHEMBL23609146 | 0.71 | HSP90AA1 (0.33) | — | |
| SCHEMBL23608933 | 0.70 | HSP90AA1 (0.31) | — | |
| SCHEMBL23876019 | 0.69 | HSP90AA1 (0.33) | — | |
| SCHEMBL29972983 | 0.67 | CYP3A4 (0.35) | — | |
| SCHEMBL23609348 | 0.67 | ALDH1A1 (0.38) | BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133689-A2 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-07-01 | — | — | WO | disclosed |