Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23609120 | 1.00 | CYP3A4 (0.35) | CYP3A4CYP2C19CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL23609210 | 0.92 | CYP3A4 (0.35) | CYP3A4CYP2C19CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL30406673 | 0.92 | CYP3A4 (0.35) | CYP3A4CYP2C19CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL30405632 | 0.90 | CYP3A4 (0.35) | CYP3A4CYP2C19CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL23609178 | 0.90 | CYP3A4 (0.35) | CYP3A4CYP2C19CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL23609187 | 0.87 | CYP3A4 (0.34) | CYP3A4CYP2C19CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL30405907 | 0.87 | CYP3A4 (0.34) | CYP3A4CYP2C19CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL23609119 | 0.83 | PDE3B (0.34) | CYP3A4CYP2C19CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL30406534 | 0.83 | PDE3B (0.34) | CYP3A4CYP2C19CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL23608947 | 0.83 | CYP3A4 (0.34) | CYP3A4CYP2C19CYP2C9CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230117592-A1 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2023-04-20 | — | — | US | disclosed |
| EP-4081199-A2 | LIPOXYGENASE INHIBITORS | SRI International (US) | 2022-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230117592-A1 | LIPOXYGENASE INHIBITORS | ALOX15B, ALOX12, ALOX5 | CYP3A4 812/4885CYP2C19 403/4885CYP2C9 554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.