Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | UGT1A4 | P22310 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25022444 | 0.83 | TSHR (0.37) | CYP19A1EGLN3TSHRPOLBMEN1 | |
| SCHEMBL13886384 | 0.80 | CYP19A1 (0.50) | CYP19A1EGLN3ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4550582 | 0.79 | EGLN3 (0.50) | CYP19A1EGLN3ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11959513 | 0.78 | EGLN3 (0.42) | CYP19A1EGLN3ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL45842 | 0.78 | — | — | |
| SCHEMBL11202609 | 0.76 | EGLN3 (0.44) | CYP19A1EGLN3ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL23875630 | 0.76 | TLR8 (0.39) | CYP19A1EGLN3ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL26045021 | 0.75 | CYP19A1 (0.43) | CYP19A1EGLN3ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13741693 | 0.75 | EGLN3 (0.46) | CYP19A1EGLN3ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10515720 | 0.74 | CYP19A1 (0.49) | CYP19A1EGLN3ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11766449-B2 | Circular RNA compositions and methods | ORNA THERAPEUTICS, INC. (US) | 2023-09-26 | — | — | US | disclosed |
| US-20230226096-A1 | CIRCULAR RNA COMPOSITIONS AND METHODS | ORNA THERAPEUTICS, INC. | 2023-07-20 | — | — | US | disclosed |
| US-11679120-B2 | Circular RNA compositions and methods | ORNA THERAPEUTICS, INC. (US) | 2023-06-20 | — | — | US | disclosed |
| US-20230058784-A1 | CIRCULAR RNA COMPOSITIONS AND METHODS | ORNA THERAPEUTICS, INC. | 2023-02-23 | — | — | US | disclosed |
| WO-2021133689-A2 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230226096-A1 | CIRCULAR RNA COMPOSITIONS AND METHODS | RTCB, HNRNPA1, HNRNPAB | CYP19A1 2822/4885EGLN3 2566/4885ALDH1A1 4484/4885 |
| US-20230058784-A1 | CIRCULAR RNA COMPOSITIONS AND METHODS | RTCB, RNGTT, HNRNPAB | CYP19A1 3057/4885EGLN3 3028/4885ALDH1A1 4532/4885 |
| US-11679120-B2 | Circular RNA compositions and methods | RTCB, HNRNPA1, HNRNPAB | CYP19A1 2822/4885EGLN3 2566/4885ALDH1A1 4484/4885 |
| US-11766449-B2 | Circular RNA compositions and methods | RTCB, RNGTT, HNRNPAB | CYP19A1 3057/4885EGLN3 3028/4885ALDH1A1 4532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.