Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3907636 | 0.81 | ALDH1A1 (0.51) | NPC1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL15823673 | 0.81 | ALDH1A1 (0.57) | NPC1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL26766823 | 0.78 | MAPK1 (0.79) | MAPK1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL29975192 | 0.78 | PTGDR2 (0.40) | MAPK1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL23579692 | 0.78 | PTGDR2 (0.40) | MAPK1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL14780242 | 0.78 | MAPK1 (0.54) | MAPK1NPC1MEN1KMT2AMAPT | |
| SCHEMBL30307389 | 0.78 | ALDH1A1 (0.56) | NPC1MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL99089 | 0.78 | ALDH1A1 (0.56) | NPC1MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL23609805 | 0.76 | GSK3B (0.47) | MAPK1NPC1MEN1KMT2AMAPT | |
| SCHEMBL18496233 | 0.73 | ALDH1A1 (0.52) | MEN1KMT2AMAPTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135316-A | Lipoxygenase inhibitors | 思研（SRI）国际顾问与咨询公司 | 2022-09-30 | — | — | CN | disclosed |
| WO-2021133689-A2 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-07-01 | — | — | WO | disclosed |