Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13753699 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL1256622 | 0.80 | MAPT (0.63) | ALDH1A1MAPTKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL31378008 | 0.80 | CD274 (0.56) | ALDH1A1MAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL23610359 | 0.80 | MPL (0.57) | ALDH1A1MAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL23610341 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL28651159 | 0.77 | MPL (0.50) | ALDH1A1MAPTKDM4ESMN1; SMN2RAB9A | |
| SCHEMBL23618156 | 0.76 | MPL (0.47) | ALDH1A1MAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL10154437 | 0.76 | MAPT (0.60) | ALDH1A1MAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL18042050 | 0.75 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4ESMN1; SMN2RAB9A | |
| SCHEMBL12495322 | 0.75 | RORB (0.53) | ALDH1A1MAPTMEN1KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240390333-A1 | NEUROPROTECTIVE COMPOSITIONS AND METHODS OF USING THE SAME | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIV AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2024-11-28 | — | — | US | disclosed |
| US-11974988-B2 | Neuroprotective compositions and methods of using the same | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2024-05-07 | — | — | US | disclosed |
| US-20210205275-A1 | NEUROPROTECTIVE COMPOSITIONS AND METHODS OF USING THE SAME | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2021-07-08 | — | — | US | disclosed |
| US-20210205275-A1 | NEUROPROTECTIVE COMPOSITIONS AND METHODS OF USING THE SAME | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2021-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210205275-A1 | NEUROPROTECTIVE COMPOSITIONS AND METHODS OF USING THE SAME | GAP43, NLN, SMN1; SMN2 | ALDH1A1 1731/4885MAPT 24/4885KDM4E 3736/4885 |
| US-11974988-B2 | Neuroprotective compositions and methods of using the same | GAP43, NLN, SMN1; SMN2 | ALDH1A1 1731/4885MAPT 24/4885KDM4E 3736/4885 |
| US-20240390333-A1 | NEUROPROTECTIVE COMPOSITIONS AND METHODS OF USING THE SAME | GAP43, NLN, SMN1; SMN2 | ALDH1A1 1731/4885MAPT 24/4885KDM4E 3736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.