Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | DBH | P09172 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | BRD2 | P25440 | 1/20 | 0.42 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.42 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27913383 | 0.76 | ALDH1A1 (0.53) | ALDH1A1KDM4EL3MBTL1HDAC8HDAC6 | |
| SCHEMBL3195921 | 0.74 | ALDH1A1 (0.52) | ALDH1A1KDM4EL3MBTL1HDAC8HDAC6 | |
| SCHEMBL27838313 | 0.74 | HDAC8 (0.61) | ALDH1A1KDM4EL3MBTL1HDAC8HDAC6 | |
| SCHEMBL8878870 | 0.74 | ALDH1A1 (0.52) | ALDH1A1KDM4EL3MBTL1HDAC8HDAC6 | |
| SCHEMBL27529223 | 0.74 | ALDH1A1 (0.52) | ALDH1A1KDM4EL3MBTL1HDAC8HDAC6 | |
| SCHEMBL27700003 | 0.72 | ALDH1A1 (0.50) | ALDH1A1KDM4EL3MBTL1HDAC8HDAC6 | |
| SCHEMBL28110914 | 0.72 | CYP11B1 (0.55) | ALDH1A1KDM4EL3MBTL1HDAC8HDAC6 | |
| SCHEMBL27944822 | 0.72 | ALDH1A1 (0.50) | ALDH1A1KDM4EL3MBTL1HDAC8HDAC6 | |
| SCHEMBL25119665 | 0.71 | HDAC8 (0.45) | ALDH1A1KDM4EL3MBTL1HDAC8HDAC6 | |
| SCHEMBL3195611 | 0.71 | HDAC8 (0.49) | ALDH1A1KDM4EL3MBTL1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4085061-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM Due, Inc. (US) | 2022-11-09 | — | — | EP | disclosed |
| CN-115279770-A | Compounds and compositions for treating diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2022-11-01 | — | — | CN | disclosed |
| WO-2021138419-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC, (US) | 2021-07-08 | — | — | WO | disclosed |