Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | NQO2 | P16083 | 3/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | METAP2 | P50579 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20475328 | 0.95 | ACHE (0.59) | ACHEMAPTKMT2AGAARAB9A | |
| SCHEMBL13271195 | 0.82 | ACHE (0.75) | ACHEMAPTKMT2AGAARAB9A | |
| SCHEMBL20475283 | 0.82 | ACHE (0.62) | ACHEMAPTKMT2AGAARAB9A | |
| SCHEMBL3181469 | 0.82 | ACHE (1.00) | ACHEMAPTKMT2AGAARAB9A | |
| Phenazine SCHEMBL29098643 | 0.80 | MAPT (0.55) | MAPTKMT2AGAARAB9AALDH1A1 | |
| SCHEMBL29645243 | 0.80 | MAPT (0.55) | MAPTKMT2AGAARAB9AALDH1A1 | |
| SCHEMBL1010318 | 0.80 | MAPT (0.55) | MAPTKMT2AGAARAB9AALDH1A1 | |
| SCHEMBL20272058 | 0.79 | ACHE (0.69) | ACHEMAPTKMT2AGAARAB9A | |
| SCHEMBL13271231 | 0.77 | ACHE (0.65) | ACHEMAPTKMT2AGAARAB9A | |
| SCHEMBL3356091 | 0.76 | ACHE (0.71) | ACHEMAPTKMT2AGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11053205-B2 | Phenazine derivatives as antimicrobial agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2021-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11053205-B2 | Phenazine derivatives as antimicrobial agents | ROS1, NOX4, PRDX3 | ACHE 970/4885MAPT 2601/4885KMT2A 3688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.