SCHEMBL23613740

SCHEMBL23613740

O=C(OCc1ccccc1)n1c(I)nc2cccnc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2B Q13224 3/20 0.46
LMNA P02545 2/20 0.44
POLB P06746 1/20 0.43
EGLN1 Q9GZT9 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
RAB9A P51151 2/20 0.41
TSHR P16473 1/20 0.41
CASP3 P42574 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
NPC1 O15118 1/20 0.40
ENPP2 Q13822 2/20 0.39
KMT2A Q03164 2/20 0.39
P2RX4 Q99571 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP2C19 P33261 1/20 0.39
TP53 P04637 1/20 0.39
CXCR3 P49682 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20669977 0.85 ALDH1A1 (0.45) GRIN2BLMNAPOLBEGLN1L3MBTL1
SCHEMBL18746208 0.82 SMN1; SMN2 (0.45) GRIN2BLMNAL3MBTL1RAB9ATSHR
SCHEMBL24514807 0.72 ALDH1A1 (0.41) LMNAL3MBTL1RAB9ASMN1; SMN2NPC1
SCHEMBL7163540 0.70 ASAH1 (0.58) LMNAL3MBTL1RAB9ASMN1; SMN2NPC1
SCHEMBL14291614 0.69 POLB (0.42) GRIN2BLMNAPOLBEGLN1L3MBTL1
SCHEMBL16341726 0.69 MEN1 (0.45) GRIN2BLMNAL3MBTL1RAB9ATSHR
SCHEMBL19820181 0.69 ALDH1A1 (0.48) GRIN2BLMNAPOLBL3MBTL1RAB9A
SCHEMBL724677 0.69 ASAH1 (0.54) LMNAL3MBTL1TSHRKMT2A
SCHEMBL3588649 0.68 TP53 (0.53) POLBRAB9ATSHRSMN1; SMN2NPC1
SCHEMBL22675703 0.68 ALDH1A1 (0.55) LMNAL3MBTL1RAB9ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220190296-A1 LIGHT-EMITTING DEVICE AND AN ELECTRONIC DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2022-06-16 US disclosed
US-11056664-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2021-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11056664-B2 Organic light-emitting device EML4, L1CAM, OR10J3 GRIN2B 124/4885LMNA 1366/4885POLB 2169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.