SCHEMBL23614520

SCHEMBL23614520

CSc1cccc(-c2cccc(C)c2)c1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.47
ACHE P22303 1/20 0.46
NR1I3 Q14994 1/20 0.42
RAB9A P51151 3/20 0.41
NPC1 O15118 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
HPGD P15428 1/20 0.40
TSHR P16473 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
ENPP3 O14638 1/20 0.40
PARP10 Q53GL7 1/20 0.39
PARP11 Q9NR21 1/20 0.39
METAP2 P50579 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PTPN5 P54829 1/20 0.39
SYK P43405 1/20 0.38
PTGS2 P35354 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL169059 0.86
SCHEMBL12947919 0.85 IDO1 (0.46) IDO1NPSR1PTPN5SYKPTGS2
SCHEMBL21507968 0.85 ENPP3 (0.46) ACHENR1I3RAB9ANPC1SMN1; SMN2
SCHEMBL18772372 0.84 IDO1 (0.40) IDO1ACHENR1I3RAB9ANPC1
SCHEMBL30849630 0.82 IDO1 (0.50) IDO1SMN1; SMN2HPGDSYKPTGS2
SCHEMBL3480820 0.82 IDO1 (0.50) IDO1SMN1; SMN2HPGDSYKPTGS2
SCHEMBL31471473 0.81 ACHE (0.69) IDO1ACHERAB9ANPC1SMN1; SMN2
SCHEMBL301247 0.81 ACHE (0.69) IDO1ACHERAB9ANPC1SMN1; SMN2
SCHEMBL29373699 0.81 ACHE (0.69) IDO1ACHERAB9ANPC1SMN1; SMN2
SCHEMBL19773528 0.79 IDO1 (0.41) IDO1SMN1; SMN2NPSR1SYKPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3845522-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE Shaanxi Lighte Optoelectronics Material Co., Ltd. (CN) 2021-07-07 EP disclosed