Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764695 | 0.78 | MIF (0.59) | KMT2AMEN1SMN1; SMN2MIFPOLB | |
| SCHEMBL7578243 | 0.78 | MIF (0.59) | KMT2AMEN1SMN1; SMN2MIFPOLB | |
| SCHEMBL31435844 | 0.74 | HSD11B1 (0.50) | PPARGPPARATAAR1HSD11B1IDO1 | |
| SCHEMBL31435841 | 0.74 | HSD11B1 (0.50) | PPARGPPARATAAR1HSD11B1IDO1 | |
| SCHEMBL16868329 | 0.71 | ALDH1A1 (0.47) | NPC1RAB9AALDH1A1PPARGPPARA | |
| SCHEMBL2423098 | 0.71 | ALDH1A1 (0.47) | NPC1RAB9AALDH1A1PPARGPPARA | |
| SCHEMBL29700303 | 0.70 | KMT2A (0.40) | OPRM1OPRD1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL17335796 | 0.69 | PIK3CA (0.51) | OPRM1OPRD1NPC1RAB9AKMT2A | |
| SCHEMBL28982569 | 0.68 | ALDH1A1 (0.45) | NPC1RAB9AALDH1A1PPARGPPARA | |
| SCHEMBL1594672 | 0.68 | TAAR1 (0.52) | KMT2APPARGPPARATAAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3845546-A1 | COMPLEXES | Johnson Matthey Public Limited Company (GB) | 2021-07-07 | — | — | EP | disclosed |