Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKE | Q14164 | 7/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 7/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 4/20 | 0.35 |
| ▸ | GABRD | O14764 | 4/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19310470 | 0.77 | GABRP (0.38) | IKBKETBK1KDM4ENPC1ABCC4 | |
| SCHEMBL12206794 | 0.75 | ADORA2A (0.36) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL18699041 | 0.75 | NAPRT (0.36) | IKBKETBK1KDM4EGABRPGABRD | |
| SCHEMBL21636943 | 0.74 | ABCC4 (0.34) | IKBKETBK1KDM4ENPC1ABCC4 | |
| SCHEMBL18287861 | 0.74 | CDK1 (0.34) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL29189702 | 0.74 | KDM4E (0.36) | IKBKETBK1KDM4EGABRPGABRD | |
| SCHEMBL24538994 | 0.74 | TET2 (0.40) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL10137844 | 0.74 | ADORA2A (0.38) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL10137834 | 0.74 | CDK1 (0.34) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL19310476 | 0.73 | LMNA (0.47) | KDM4EABCC4PKMRAB9AGABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230043577-A1 | METHOD FOR DETERMINING 5-METHYLCYTOSINE CONFIGURATIONS IN DNA | TECHNISCHE UNIVERSITAET DORTMUND (DE) | 2023-02-09 | — | — | US | disclosed |
| US-20210324436-A1 | METHODS AND REAGENTS FOR SYNTHESISING POLYNUCLEOTIDE MOLECULES | OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) | 2021-10-21 | — | — | US | disclosed |
| EP-3845554-A1 | METHOD FOR DETERMINING 5-METHYLCYTOSINE CONFIGURATIONS IN DNA | Technische Universität Dortmund (DE) | 2021-07-07 | — | — | EP | disclosed |