Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3229730 | 0.71 | ALDH1A1 (0.44) | ALDH1A1TSHRFFAR3LMNA | |
| SCHEMBL9174262 | 0.70 | ALDH1A1 (0.42) | ALDH1A1TSHRFFAR3LMNA | |
| SCHEMBL10193631 | 0.69 | FFAR3 (0.36) | ALDH1A1FFAR3 | |
| Bicarbonate SCHEMBL980934 | 0.69 | ALDH1A1 (0.46) | ALDH1A1TSHRFFAR3LMNA | |
| SCHEMBL10344061 | 0.68 | ALDH1A1 (0.47) | ALDH1A1TSHR | |
| SCHEMBL10344060 | 0.68 | ALDH1A1 (0.47) | ALDH1A1TSHR | |
| SCHEMBL16082013 | 0.67 | FFAR3 (0.31) | FFAR3 | |
| SCHEMBL9171301 | 0.65 | ALDH1A1 (0.38) | ALDH1A1TSHR | |
| SCHEMBL28420020 | 0.65 | ALDH1A1 (0.42) | ALDH1A1TSHRLMNA | |
| SCHEMBL20979898 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3928836-A1 | N-SUBSTITUTED INDOLE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | Idorsia Pharmaceuticals Ltd (CH) | 2021-12-29 | — | — | EP | disclosed |
| EP-3625228-B1 | PYRIMIDINE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-07-07 | — | — | EP | disclosed |