Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10344061 | 0.74 | ALDH1A1 (0.47) | ALDH1A1TSHR | |
| SCHEMBL10344060 | 0.74 | ALDH1A1 (0.47) | ALDH1A1TSHR | |
| SCHEMBL3766034 | 0.73 | TSHR (0.39) | ALDH1A1TSHRHPGD | |
| SCHEMBL3229730 | 0.73 | ALDH1A1 (0.44) | ALDH1A1TSHRFFAR3LMNAHPGD | |
| SCHEMBL3766031 | 0.73 | TSHR (0.39) | ALDH1A1TSHRHPGD | |
| SCHEMBL9174262 | 0.71 | ALDH1A1 (0.42) | ALDH1A1TSHRFFAR3LMNATDP1 | |
| Propionic Acid SCHEMBL27683338 | 0.70 | FFAR3 (0.59) | ALDH1A1TSHRFFAR3LMNAHPGD | |
| Bicarbonate SCHEMBL982714 | 0.69 | TSHR (0.50) | ALDH1A1TSHRFFAR3LMNAHPGD | |
| SCHEMBL23615907 | 0.69 | ALDH1A1 (0.39) | ALDH1A1TSHRFFAR3LMNA | |
| Acrylic Acid SCHEMBL30150339 | 0.67 | FFAR3 (0.62) | ALDH1A1TSHRFFAR3LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1892789-B1 | LITHIUM SECONDARY BATTERY | MITSUBISHI CHEM CORP (JP) | 2018-02-28 | — | — | EP | disclosed |
| US-20110014504-A1 | LITHIUM SECONDARY BATTERY | MITSUBISHI CHEMICAL CORPORATION (JP) | 2011-01-20 | — | — | US | disclosed |
| US-20080311478-A1 | Lithium Secondary Battery | MITSUBISHI CHEMICAL CORPORATION (JP) | 2008-12-18 | — | — | US | disclosed |
| EP-1892789-A1 | LITHIUM SECONDARY BATTERY | Mitsubishi Chemical Corporation (JP) | 2008-02-27 | — | — | EP | disclosed |