Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3738416 | 0.76 | MEN1 (0.41) | MEN1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL20870669 | 0.72 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL7025994 | 0.71 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1LMNAHSD17B10 | |
| Acrylic Acid SCHEMBL28456925 | 0.68 | CHRNB2 (0.42) | ALDH1A1LMNAHSD17B10HPGDTSHR | |
| SCHEMBL9719706 | 0.67 | — | — | |
| SCHEMBL17384735 | 0.67 | MEN1 (0.47) | MEN1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL27580489 | 0.67 | TSHR (0.42) | MEN1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL20868585 | 0.66 | KMT2A (0.42) | MEN1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL5410926 | 0.66 | SOAT1 (0.41) | MEN1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL8927958 | 0.65 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3687506-B1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARM INC (US) | 2021-07-07 | — | — | EP | disclosed |