Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.33 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.33 |
| ▸ | SLC26A3 | P40879 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21437548 | 0.90 | MRGPRX4 (0.37) | ALDH1A1MEN1KMT2AMRGPRX4MAOB | |
| SCHEMBL21438656 | 0.84 | CXCR2 (0.32) | MRGPRX4MAOBPOLBEPHX2PPARG | |
| SCHEMBL21437936 | 0.83 | CFD (0.38) | MRGPRX4MAOBSLC26A3 | |
| SCHEMBL21438516 | 0.82 | CFD (0.45) | MRGPRX4MAOBSLC26A3 | |
| SCHEMBL30009799 | 0.82 | MRGPRX4 (0.39) | MRGPRX4MAOBPOLBEPHX2PPARG | |
| SCHEMBL31026075 | 0.82 | MRGPRX4 (0.39) | MRGPRX4MAOBPOLBEPHX2PPARG | |
| SCHEMBL21438098 | 0.82 | MRGPRX4 (0.39) | MRGPRX4MAOBPOLBEPHX2PPARG | |
| SCHEMBL29634143 | 0.81 | SLC26A3 (0.35) | ALDH1A1MEN1KMT2AMRGPRX4POLB | |
| SCHEMBL21438449 | 0.81 | SLC26A3 (0.35) | ALDH1A1MEN1KMT2AMRGPRX4POLB | |
| SCHEMBL21455469 | 0.81 | CFD (0.38) | ALDH1A1MAOBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3687506-B1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARM INC (US) | 2021-07-07 | — | — | EP | disclosed |