Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20487435 | 0.76 | ALOX15 (0.53) | ALOX15GFERADAM17ATMALDH1A1 | |
| SCHEMBL20491355 | 0.76 | ALOX15 (0.56) | ALOX15GFERADAM17ATMALDH1A1 | |
| SCHEMBL10883891 | 0.76 | HDAC3 (0.60) | ALOX15GFERADAM17ATMALDH1A1 | |
| SCHEMBL5804126 | 0.76 | HDAC3 (0.59) | ALOX15GFERADAM17ATMALDH1A1 | |
| SCHEMBL1856302 | 0.76 | GSK3B (0.59) | ALOX15GFERADAM17ATMALDH1A1 | |
| SCHEMBL5804124 | 0.76 | HDAC3 (0.56) | ALOX15GFERADAM17ATMALDH1A1 | |
| SCHEMBL9618651 | 0.75 | ALOX15 (0.51) | ALOX15GFERADAM17ATMALDH1A1 | |
| SCHEMBL22728863 | 0.74 | ALOX15 (0.47) | ALOX15GFERADAM17ATMALDH1A1 | |
| SCHEMBL10455298 | 0.73 | HDAC3 (0.54) | ALOX15GFERADAM17ATMALDH1A1 | |
| SCHEMBL19642631 | 0.73 | ATM (0.54) | ALOX15GFERADAM17ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3589630-B1 | CYCLIC SULFAMIDE COMPOUNDS AND METHODS OF USING SAME | ASSEMBLY BIOSCIENCES INC (US) | 2021-07-07 | — | — | EP | disclosed |