Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | TPMT | P51580 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902751 | 0.84 | CA12 (0.45) | TPMTKDM4EALDH1A1CYP3A4MAPK1 | |
| SCHEMBL21437827 | 0.82 | TPMT (0.47) | TTRTPMTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL23616986 | 0.81 | ALDH1A1 (0.46) | KDM4EALDH1A1CYP1A2CYP3A4MAOA | |
| SCHEMBL23617246 | 0.77 | MAPT (0.50) | TTRTPMTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL23617314 | 0.77 | MAOB (0.58) | TTRKDM4EALDH1A1MAOAMEN1 | |
| SCHEMBL28354314 | 0.73 | CYP3A4 (0.39) | KDM4EALDH1A1CYP1A2CYP3A4MAOA | |
| SCHEMBL12302085 | 0.71 | CA1 (0.44) | KDM4EALDH1A1CYP1A2CYP3A4MAOA | |
| SCHEMBL566569 | 0.70 | TP53 (0.52) | TTRKDM4EALDH1A1HRH3CA12 | |
| SCHEMBL20562778 | 0.70 | ALDH1A1 (0.42) | KDM4EALDH1A1CYP1A2CYP3A4MAOA | |
| SCHEMBL11329835 | 0.69 | TTR (0.54) | TTRTPMTKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3687506-B1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARM INC (US) | 2021-07-07 | — | — | EP | disclosed |